Members of the Der Lab recently volunteered to cook dinner at SECU Family House in Chapel Hill. SECU Family House is a safe, nurturing, affordable home for patients and their loved ones who travel great distances to UNC Hospitals for life-saving procedures and serious illnesses. They help people across North Carolina and beyond in times … Continue reading Der Lab Volunteers at Family House
Raising pancreatic cancer awareness can be done as an individual or group all year long, but it is especially important during Pancreatic Cancer Awareness Month in November. During this month, we in the Der Lab are taking time to promote the Pancreatic Cancer Action Network's initiative to Demand Better. For Patients. For Survival. On November 16th, which … Continue reading World Pancreatic Cancer Day is November 16
UNC Lineberger’s Channing Der, PhD, and colleagues have made new findings that could help researchers identify treatments for cancers with mutations in the RAS gene family, which are among the most highly mutated genes in cancer.
Der Lab postdoc, Angelina Vaseva ,was awarded a 2017 Women in Cancer Research Scholar Award. AACR-WICR Scholar Awards are awarded to members of Women in Cancer Research who are scientists-in-training and presenters of meritorious scientific papers at AACR Annual Meetings. To learn more about these awards visit: http://www.aacr.org/Meetings/Pages/Travel%20Grants/women-in-cancer-research-scholar-awards.aspx#.WRMsslXyvIU
On May 4, Dr. Der was the keynote speaker at the 4th Annual Biological Sciences Symposium at UNC Charlotte. This event was sponsored by the Association of Biological Sciences Graduate Students (ABSGS) at the University of North Carolina at Charlotte. Dr. Der's talk was titled "Targeting Ras for cancer treatment: Know your enemy".
The Running RAScals (aka the Der Lab at UNC Lineberger & Friends) participated in this year’s PanCAN #PurpleStride run on Saturday. This 5k run raises money to support the Pancreatic Cancer Action Network. The team, organized by Kirsten Bryant, raised $12,998 to support Pancreatic Cancer Research, coming in Second in overall fundraising!
This past Saturday several members of the Der Lab participated in the Tar Heel 10 Miler. The Tar Heel 10 Miler benefits the UNC Lineberger Comprehensive Cancer Center and the Chapel Hill-Carrboro YMCA’s We Build People Campaign. The lab runners included postdocs Kirsten Bryant, Clint Stalnecker, Andrew Waters, and Bjoern Papke, graduate student Nate Diehl, and … Continue reading Der Lab Participates in Tar Heel 10 Miler
In the recently published review “Drugging Ras: Know your enemy” Bjoern Papke and Channing Der summarize the latest efforts in targeting the Ras oncogene. The review was part of the special review series “Frontiers in Cancer Therapy”. http://science.sciencemag.org/content/355/6330/1158
Channing Der presented a plenary lecture at the 36th Annual Conference of Indian Association for Cancer Research on: The 21st Century - War on Cancer, February 9-11, 2017, Amala Cancer Research Centre, Thrissur, Kerala, India.
Abstract The KRAS GTPase plays a critical role in control of cellular growth. The activity of KRAS is regulated by guanine nucleotide exchange factors (GEFs), GTPase-activating proteins (GAPs), and also by posttranslational modification. Lysine 104 in KRAS can be modified by ubiquitylation and acetylation, but the role this residue in intrinsic KRAS function has not … Continue reading George and Huynh were authors on a research study that evaluated the role of posttranslational modifications in regulating KRAS oncogene function.