Channing Der guides the Guardian through the history of the "Undruggable RAS Mutation."
UNC Lineberger’s Channing Der, PhD, and Antje Schaefer, PhD. UNC UNC Lineberger's Channing Der, Ph.D. Sarah Graham Kenan Distinguished Professor in the UNC School of Medicine Department of Pharmacology was the co-corresponding author of a paper published in Cancer Discovery. Antje Schaefer, Ph.D., research assistant professor in the UNC School of Medicine Department of Pharmacology, … Continue reading Der Lab Publishes in Cancer Discovery
December 15, 2019 On Sunday, the Der lab prepared a taco bar for the guests at the Family House. Together, they made ground beef, rice, beans, vegetables, and homemade pico de gallo served in soft tacos, as well as cookies and sweet tea. The Der lab also had the opportunity to sit down and eat … Continue reading Der Lab Volunteers at SECU Family House
For the month of November, the Der and Cox labs have gone purely purple. The dress code is inspired by the official pancreatic cancer ribbon and is worn all month to bring awareness to pancreatic cancer. See ABC 11's interview with Dr. Jen Jen Yeh and Dr. Kirsten Bryant here. Photos courtesy of the UNC … Continue reading Der Lab Goes Purple for Pancreatic Awareness
A new study from University of North Carolina Lineberger Comprehensive Cancer Center researchers reveals important findings about how a common genetic mutation in pancreatic cancer works to drive tumor growth. In the journal Cancer Discovery, researchers led by UNC Lineberger’s Channing Der, PhD, and Aaron Hobbs, PhD, reported details of the role of a particular mutation … Continue reading Researchers find KRAS gene mutation differences have implications for pancreatic cancer treatment
Right DirectionThe findings follow data this summer that showed half of those treated with Amgen’s drug at a wide range of doses responded. The latest results more than doubled the number of patients treated with the highest dose and tracked them for three more months. It’s too early to know how long the benefits will last and … Continue reading Channing Der Quoted by Bloomberg
Congratulations to Irem Dagliyan for successfully passing her doctoral defense! Irem presented Low dose vertical inhibition of ERK MAPK cascade for the treatment of KRAS-mutant cancer in 4007 Genetic Medicine Building. Afterword, she celebrated her success with her labmates, friends, and family. We are excited for Irem to begin her new journey as Dr. Irem Dagliyan! … Continue reading Congratulations, Dr. Irem Dagliyan!
August 5, 2019 Today, the Der and Cox labs were visited by the Blue Ribbon group of Wilmington, NC. The Blue Ribbon Run raises money for the Julie M. Brown and Christina M. Gianoplus Fund for Colon Cancer Research from Wilmington, NC. Members of the group included Ana Boudreau, event founder, and Sarah Powell, a … Continue reading Der Lab Blue Ribbon Tour 2019
This year lab members Antje Schaefer and Andrew Waters presented at the FASEB: Regulation and Function of Small GTPases Conference in Olean, New York. Antje's presentation, pictured below, was on "The gain-of-function mutation Y42C in RHOA promotes FAK activation and dependency in diffuse gastric cancer."
This summer, the Der, Cox, Campbell, and Counter labs visited Emerald Isle, NC. Together they spent three days giving talks, getting to know one another, and discussing upcoming projects.