Mutant RAS-driven cancers are infamously resistant to chemotherapeutics. Reporting in Cell, Grabocka and Bar-Sagi (2016) demonstrate that when subjected to stress, mutant KRAS-dependent lipid production leads to upregulated stress granule formation. This confers not only cell-autonomous cytoprotection but also paracrine establishment of a stress-resistant tumor niche. Mutant RAS Calms Stressed-Out Cancer Cells. Bryant KL, Der CJ. Dev Cell. … Continue reading Kirsten Bryant authored a review in Cancer Cell, highlighting studies by Bar-Sagi and colleagues published in Cell.
World Pancreatic Cancer Day
The Der Lab has gone purple for the entire month of November for Pancreatic Cancer Awareness Month! Every day they wear purple they are raising money for the Pancreatic Cancer Action Network. Yesterday, November 17, was World Pancreatic Cancer Day and the lab spent the day showing their support for Pancreatic Cancer Research all day. See … Continue reading World Pancreatic Cancer Day
Experts in Pancreatic Cancer and KRAS Discuss Tough Questions
The Pancreatic Cancer Action Network (PanCAN) has recently released videos featuring Channing Der and Kirsten Bryant, as a part of their effort to raise awareness about Pancreatic Cancer.
UNC Lineberger faculty, trainees advocate for federal support for research
Several UNC Lineberger Comprehensive Cancer Center faculty and trainees were in Washington D.C. Thursday as part of as the Rally for Medical Research, a national campaign that advocates for sustained and strong federal funding for medical research. The American Association for Cancer Research founded the annual event in 2013. AACR expected more than 300 scientists, … Continue reading UNC Lineberger faculty, trainees advocate for federal support for research
Der Lab members attend PanCAN Annual Meeting
Channing, Kirsten and Bjoern attended the Pancreatic Cancer Action Network Annual Scientific Meeting in San Diego, CA, August 18-21, 2016. The theme for this meeting was Wage Hope 2020 with the goal of doubling the dismay 5-year survival rate for this deadly cancer. This meeting was held jointly with the The Pancreatic Cancer Action … Continue reading Der Lab members attend PanCAN Annual Meeting
Der, Cox, and Bryant headed to The Hill for Advocacy Day
Drs. Der, Cox, and Bryant headed to DC June 20 & 21 to support encourage the nations congressmen and women that Pancreatic Cancer research funding needs to be a priority in the US budget. The picture below is Dr. Der meeting with Senator Roger Wicker of Mississippi.
Bjoern Papke awarded the Otto Hahn Medal
Bjoern Papke, a postdoctoral research fellow in the Der lab, was recently awarded the Otto Hahn Medal from the Max Planck Society in Germany. The Otto Hahn Medal is given to junior scientists in recognition of their outstanding scientific achievements during their time as a PhD student. Bjoern did his PhD in the lab of … Continue reading Bjoern Papke awarded the Otto Hahn Medal
Kirsten Bryant Celebrates Father’s Day by Advocating for Her Dad
As a child, Kirsten Bryant, PhD, used to follow her dad around everywhere. One of his favorite pastimes was working in the yard, and Bryant would be seen pushing a toy wheelbarrow alongside her dad as he tended to their gardens in Womelsdorf, Conn. She would even take naps in the flowerbeds to be near him while he was gardening.
Stubborn Death Rate Spurs Calls for Fresh Focus on Pancreatic Cancer
The problem with pancreatic cancer is there aren’t very many simple questions to answer, and I think this discourages people from joining the field because you need to be generating results to get grants.
Der honored with Emmanuel Farber Distinguished Visiting Lectureship
Dr. Channing Der was honored as this year's Emmanuel Farber Distinguished Visiting Lecturer. This special talk is a part of the University of Toronto Laboratory Medicine & Pathobiology weekly seminar. Dr. Der spoke about Targeting RAS for cancer treatment. See below for the history of this special lectureship. History of the Farber Distinguished Visiting Lecture … Continue reading Der honored with Emmanuel Farber Distinguished Visiting Lectureship
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