Promising direction for the treatment of pancreatic cancers driven by KRAS mutation

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found a promising strategy that may limit the growth of pancreatic cancers in patients with a mutation in a gene called KRAS. More than 95 percent of pancreatic cancers have KRAS mutations, and there's strong evidence that blocking the gene's function could be a very … Continue reading Promising direction for the treatment of pancreatic cancers driven by KRAS mutation

Cox and Der lead team to $2M+ NCI U01 grant

A research team led by Drs. Adrienne D. Cox and Channing J. Der (members of the UNC Lineberger Program in Molecular Therapeutics) is one of the first recipients of an NCI U01 grant on New Approaches to Synthetic Lethality for Mutant KRas-Dependent Cancers. Their team, which also includes Drs. Ben Major at UNC, Kris Wood … Continue reading Cox and Der lead team to $2M+ NCI U01 grant

2015 Ras Beach Retreat

Members of the Der, Cox and Campbell labs at UNC Lineberger Comprehensive Cancer Center and members of the Wood, Onaitis, and Counter labs at Duke University, the Kashatus Lab at University of Virginia, and the Lim Lab at Washington University St. Louis came together at Emerald Isle for their annual scientific retreat July 26-29. Monday, July 27 9:00-9:20        Minu Ramanan (Campbell lab) … Continue reading 2015 Ras Beach Retreat

Der Lab Collaborator Featured on Cover of Genes & Cancer

Lauren Huff, a member of Dr. Adrienne Cox's lab at UNC Lineberger and frequent collaborator of the Der lab, is featured on the latest issue of Genes & Cancer (Nov/Dec 2013). Lauren successfully defended her thesis November 4, 2013. She is the first author of the following article. The Role of Ect2 Nuclear RhoGEF Activity … Continue reading Der Lab Collaborator Featured on Cover of Genes & Cancer